Holmes, Margaret and Poe's Brooklyn-based detective agency solves the crimes no one else can. Or they did - until Holmes decided to leave the business. There is no time to waste as the team are called to a fresh NYPD crime scene - and tasked with looking into the disappearance of six infants. Time is ticking as they work to unravel the mystery. But they need Holmes. If they're going to solve the crime of the century, first they must save their friend.